Surface-enhanced Raman scattering nanotags for bioimaging

Surface-enhanced Raman scattering (SERS) technique has shown extraordinary features for biomedical applications. The implementation of SERS nanotags opened a new era bioimaging and detections. As powerful tool, provide favorable properties such as fingerprint spectrum, narrow peak linewidth, good photostability, high spatial resolution accompanied by various rational designs nanoparticles. They have proven useful imaging agents in vivo, ex vitro detection cancerous cells tissues. This tutorial provides the basic principles nanotags, including recent progress SERS-based applications, well outlooks into future developments toward practical clinical SERS.